Understanding Cervical Cancer: Causes Symptoms and Risks Factors

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The cervix, a vital component of the female reproductive system, plays a crucial role in connecting the lower part of the uterus to the vagina, forming the birth canal. When abnormalities arise in the cells of the cervix, it can lead to cervical cancer—a formidable adversary that, if left undetected, can infiltrate deeper tissues and metastasize to critical organs such as the bladder, vagina, lungs, and liver.

Understanding Cervical Cancer Origins

Cervical cancer begins its insidious journey on the surface of the cervix. The transformation of normal cells into precancerous ones marks the onset of this condition. Without early detection, the cancer can progress, extending its reach to the deeper layers of the cervix and potentially spreading to distant organs.

Cervical cancer can manifest in two primary locations: the ectocervix, visible in the vagina, and the endocervix, the canal linking the vagina to the uterus. The two primary types of cervical cancer are squamous cell carcinoma and adenocarcinoma, with squamous cell carcinoma accounting for 80% to 90% of cases, and adenocarcinoma constituting 10% to 20%.

Causes of Cervical Cancer: Unraveling the Complex Web

Human Papillomavirus (HPV) Infection: The predominant cause of cervical cancer is the sexually transmitted human papillomavirus (HPV). This virus, notorious for causing genital warts, is responsible for the majority of cervical cancer cases.

Immune System Deficiency: Women with compromised immune systems face an elevated risk of cervical cancer. Of the 100 HPV strains, HPV-16 and HPV-18 are the most implicated in cervical cancer. However, it’s crucial to note that the presence of a cancer-causing strain does not guarantee the development of cervical cancer. The immune system often clears the majority of HPV infections within two years.

Additional Risk Factors: Women infected with HIV, tobacco smokers, those with multiple sexual partners, and individuals with prolonged use of oral contraceptives face an increased risk of cervical cancer. These factors contribute to heightened exposure to HPV and potential complications.

Socioeconomic Factors: Cervical cancer exhibits a concerning correlation with socioeconomic status. Individuals with limited access to cervical cancer screening are at a higher risk. Addressing these disparities is crucial for effective prevention and early intervention.

Cervical Cancer Symptoms: Decoding the Early Warnings

In the initial stages, cervical cancer may stealthily progress without manifesting symptoms. However, as the disease advances, the following early signs may emerge:

●       Pain and Discomfort during Intercourse: Unexplained discomfort during sexual activity can signal the presence of cervical cancer.

●       Unusual Vaginal Bleeding: Irregular bleeding, whether post-intercourse, between periods, after menopause, or following a pelvic examination, warrants attention.

●       Unusual Vaginal Discharge: Watery, bloody, or foul-smelling vaginal discharge can be indicative of cervical cancer.

As cancer metastasizes, symptoms can include pelvic pain, difficulty in passing urine, swelling of the feet, renal failure, bone pain and fractures, weight loss, loss of appetite, easy fatigability, backache, and stomach pain.

Conclusion: Empowering Through Knowledge

This exploration into cervical cancer aims to empower individuals with knowledge, fostering awareness and understanding of its causes, symptoms, and associated risks. Early detection through regular screenings, coupled with addressing risk factors and promoting accessibility to healthcare, stands as our collective shield against the impact of cervical cancer. As we delve deeper into research and prevention strategies, the journey towards minimizing the prevalence of cervical cancer remains an ongoing imperative.

Shared by: Dr Meenal Patvekar, 
                   Professor Dr. D. Y. Patil Medical College, Hospital and Research Centre, Pimpri, Pune

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